Project Description

DNA Finger printing Course:

DNA Fingerprinting, also termed as DNA Profiling, Genotyping, DNA Typing or Genetic Fingerprinting is one of the most recent advancements in Forensic Science. This technique was discovered by Sir. Alec Jeffreys. While going through this network, he noticed that certain sequences of highly variable DNA (known as minisatellites), do not contribute to the functions of genes, and are repeated within genes. Jeffreys recognized that each individual has a unique pattern of minisatellites (the only exceptions being multiple individuals from a single zygote, such as identical twins). For the extraction of DNA, a sample of cells such as skin, hair, blood, saliva etc. is required.

According to this technique, the DNA is extracted from the cells of skin, hair, blood, saliva etc., and then it is purified. Jeffrey’s original approach was based on Restriction Fragment Length Polymorphism (RFLP). In the RFLP technology, the DNA was cut at specific points along the strand with proteins known as restriction enzymes. The enzymes produced fragments of varying lengths that were sorted by placing them on a gel and then subjecting the gel to an electric current (electrophoresis): the shorter the fragment, the more quickly it moved toward the positive pole (anode). The sorted double-stranded DNA fragments were then subjected to a blotting technique in which they were split into single strands and transferred to a nylon sheet.

The fragments underwent autoradiography in which they were exposed to DNA probes—pieces of synthetic DNA that were made radioactive and that bound to the minisatellites. A piece of X-ray film was then exposed to the fragments, and a dark mark was produced at any point where a radioactive probe had become attached. The resultant pattern of marks could then be analysed. Other than RFLP, Polymerase Chain Reaction (PCR), Short Tandem Repeats (STR) and Variable Number Tandem Repeats are also used for the analysis procedure.

DNA Fingerprinting technique is used in cases of sexual assaults, missing persons, paternity-maternity issues and certain other criminal cases. This course structure would make the students aware of the complex techniques and analytical methods employed by the scientists in DNA Profiling, and the revolution that the discovery of DNA Fingerprinting brought into the criminal investigation system.

This course is a hands-on training of both theoretical background as well as practical skills development on state-of the art machinery used by forensic laboratories around the world.

Sub Module: Inheritance testing

In this module you will discover different types of genetic inheritance and understand genomic testing.
Genomics is an ever-developing area of healthcare, research and genetic tests are being mainstreamed, becoming more accessible than ever before. That’s why it’s important for professionalsinvestigators and lab technicians to obtain in depth knowledge and skills to understand genetic inheritance so they can provide appropriate quality service to public or clients.

Syllabus
Welcome to the course
1- The principles of genetic inheritance in healthcare
2- Patterns of inheritance Part 1
3- Patterns of inheritance Part 2
4- The practicalities of taking a family history and recognising deviations
5- The principles of pedigree drawing
6- Additional considerations to genetic inheritance and testing
7- Standardising protocols and procedures across investigative services

To be eligible for the Introduction to Forensic Criminal Investigation professional CPD course, you should normally be working in the field and wish to enhance or improve your knowledge and skill base.

English proficiency:
Candidates must be able to read and write at a proficient level to pursue the course.
Alternatively, a letter to show that the Medium of Instruction was in English for your prior education or and work environment.

We also offer an internal English test for applicants who are unable to provide the above evidence of English proficiency.

At Campus Total fee: £3,500/

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